Speaker
Dr
Oskar Berntsson
(University of Gothenburg)
Description
The function of proteins is closely linked to their structure. Protein structures, however, are not static but rather dynamic and increased understanding of these structural dynamics is crucial for increased understanding of proteins. We have employed time-resolved X-ray solution scattering as a direct structural probe to study the signal transduction in different photoreceptor proteins. We have investigated members of the red-light sensing phytochromes, the blue light sensing cryptochromes and proteins with blue light sensing light-oxygen-voltage domains. Coupled with molecular dynamics simulations these investigations have revealed new information on how chemical changes at the light absorbing chromophore affects the global structure of the photoreceptor, in order to relay the signal further.
Primary author
Dr
Oskar Berntsson
(University of Gothenburg)
Co-author
Dr
Sebastian Westenhoff
(University of Gothenburg)
